Medicaid Coverage for Prescription Medications: What’s Included in 2025

Medicaid Coverage for Prescription Medications: What’s Included in 2025
by Derek Carão on 22.12.2025

When you’re on Medicaid, getting your prescriptions shouldn’t mean choosing between medicine and rent. But knowing what’s covered - and what’s not - can feel like navigating a maze. In 2025, Medicaid covers outpatient prescription drugs for nearly 85 million low-income Americans, but the details vary wildly by state. Some states make it easy. Others make you jump through hoops. Here’s what you actually need to know.

Medicaid Covers Prescriptions - But Not All of Them

Federal law doesn’t require Medicaid to pay for prescription drugs, but every single state does. That’s because covering medications saves money in the long run. A person with diabetes who can’t afford insulin ends up in the ER. A person with high blood pressure who skips pills risks a stroke. Medicaid knows this. So it pays for meds - mostly.

But not every drug is on the list. Each state creates its own Preferred Drug List (PDL), which sorts medications into tiers. Tier 1 is usually generic drugs with the lowest copay. Tier 2 is brand-name drugs with higher costs. Tier 3? That’s often specialty drugs - expensive ones for conditions like rheumatoid arthritis or hepatitis C.

For example, in North Carolina, a generic blood pressure pill might cost $3. A brand-name version? $25. And a specialty drug for multiple sclerosis? You could pay $100 or more - unless you qualify for extra help.

Step Therapy: You Have to Fail First

One of the biggest surprises for new Medicaid beneficiaries? You might not get the drug your doctor prescribed right away. Many states require step therapy - also called "trial and failure." Here’s how it works: Your doctor prescribes Drug A. But Medicaid’s formulary says Drug B is preferred. So you have to try Drug B first. If it doesn’t work - or causes side effects - you try Drug C. Only after failing two preferred drugs can you get Drug A. And yes, that’s legal.

North Carolina requires this for most chronic conditions. Florida does too. So do 38 other states. The idea? Save money by pushing cheaper, proven drugs first. But the reality? People wait. Sometimes for weeks.

A 2024 survey by the Medicare Rights Center found that 63% of Medicaid beneficiaries faced delays because of step therapy. One Reddit user in North Carolina wrote: "I had to try three SSRIs before they’d approve Wellbutrin. My depression got worse. I missed work. I cried every day waiting for approval."

Prior Authorization: Paperwork That Can Delay Care

Even if a drug is on the formulary, you might still need prior authorization. That means your doctor has to submit paperwork - often including lab results, diagnosis codes, and proof you tried other drugs - before Medicaid will pay.

Some drugs require it every time. Others only once, for up to three years. In North Carolina, people with Type 1 Diabetes using premixed insulin can get a prior authorization that lasts three years. But if you switch to a different insulin, you start over.

The process isn’t fast. The average approval takes 7.2 business days. If it’s denied? You appeal. That takes another 14.5 days on average. But here’s the good news: 78% of denials get overturned when your doctor submits full clinical notes. Don’t give up. Push back. Ask your doctor to write a detailed letter explaining why the preferred drug won’t work for you.

Doctor and patient in clinic, surrounded by swirling paperwork and a prior authorization alert.

Costs: Copays, Deductibles, and the Extra Help Program

Medicaid doesn’t charge premiums for most enrollees. But copays? They exist - and they vary.

- Generics: Usually $1-$5 - Brand-name drugs: $5-$25 - Specialty drugs: $50-$150, sometimes more

But if you qualify for Extra Help (also called the Low-Income Subsidy), your costs drop dramatically. In 2025:

- $0 monthly premium - $0 deductible - $4.90 copay for generics - $12.15 for brand-name drugs - After you spend $2,000 total on drugs in a year? You pay $0 for everything else.

Here’s the catch: If you have full Medicaid coverage, you automatically qualify for Extra Help. But 1.2 million people who are eligible don’t know it. Check with your state Medicaid office or call 1-800-MEDICARE. Don’t assume you’re not eligible.

What’s Not Covered? The Hidden Gaps

Not every drug makes the list. States remove medications all the time - usually because they no longer offer rebates or cost too much.

In North Carolina’s October 2025 formulary update, these drugs were dropped:

- Vasotec Tablet - Acanya Cream - Trulance Tablet - Vanos Cream - Solodyn ER Tablet - Apriso Capsule Some were removed because manufacturers stopped offering rebates. Others? They were replaced with cheaper alternatives. If your drug disappeared from the formulary, your doctor can request an exception - but it’s not guaranteed.

Also, over-the-counter drugs? Generally not covered. Unless you have a prescription for them. And even then, it’s rare.

Network Pharmacies and Mail Order

You can’t just walk into any pharmacy. Medicaid works with specific network pharmacies. CVS, Walgreens, Rite Aid - most are in. But small local pharmacies? Not always.

For maintenance meds (like blood pressure or diabetes pills), many states push you toward mail-order services. You get a 90-day supply shipped to your house - often at a lower cost. But if you’re not comfortable with mail order, you can usually still use a local pharmacy. Just confirm they’re in-network first.

Family receives mail-order medication at night, glowing Extra Help badge on their door.

How to Find Your State’s Formulary

There’s no national Medicaid formulary. You need your state’s. Here’s how:

1. Go to your state’s Medicaid website (search "[Your State] Medicaid formulary") 2. Look for "Preferred Drug List" or "PDL" 3. Download the PDF - it’s usually updated every 3-6 months 4. Search your drug by name or generic ingredient 5. Check the tier and any restrictions (step therapy, prior auth)

If you’re stuck, call your state’s Medicaid helpline. Or find a local SHIP counselor (State Health Insurance Assistance Program). They help people navigate this stuff every day.

What’s Changing in 2025-2026?

New rules are coming. In September 2025, CMS announced it will require states to prove their formularies don’t block access to medically necessary drugs. That’s a big shift. For years, states could restrict drugs without showing harm. Now, they’ll have to justify it.

Also, the Inflation Reduction Act’s $2,000 out-of-pocket cap for Medicare Part D now applies to dual-eligible beneficiaries (those on both Medicare and Medicaid). That means if you’re on both programs, your drug costs are capped - even if your state’s Medicaid formulary is strict.

And experts predict more gene therapies will hit the market by 2027 - each costing over $2 million. Medicaid programs are already testing new payment models to handle these drugs without bankrupting budgets.

What to Do Right Now

If you’re on Medicaid and take prescriptions:

- Know your state’s formulary. Check it every six months - they change often. - Ask your doctor: "Is this drug on the PDL? Do I need prior auth?" - If your drug was removed or denied, ask for a formulary exception. Bring your doctor’s note. - If you’re paying more than $5 for generics or $25 for brands, ask if you qualify for Extra Help. - Use mail-order for maintenance meds to save money and time. - Keep copies of all prior auth approvals and denials.

Medicaid isn’t perfect. But it’s the biggest safety net we have for low-income Americans needing prescriptions. Understanding how it works - the tiers, the steps, the paperwork - means you’re not just a patient. You’re an advocate.

Does Medicaid cover all prescription drugs?

No. Medicaid covers most outpatient prescription drugs, but each state creates its own Preferred Drug List (PDL). Some drugs are excluded because they don’t offer rebates, are too expensive, or have cheaper alternatives. Always check your state’s current formulary before assuming a drug is covered.

What is step therapy in Medicaid?

Step therapy means you must try and fail on one or two lower-cost, preferred drugs before Medicaid will cover the one your doctor prescribed. For example, if your doctor prescribes a brand-name antidepressant, you may first need to try two generic options. This rule exists in 38 states and can cause delays in treatment.

How do I get prior authorization for a drug?

Your doctor must submit paperwork to your state’s Medicaid program or pharmacy benefit manager (PBM). This usually includes your diagnosis, why preferred drugs won’t work, and sometimes lab results. The process takes 7-14 days. If denied, appeal with more clinical documentation - 78% of appeals are approved when complete.

Can I use any pharmacy with Medicaid?

No. You must use a pharmacy in your state’s Medicaid network. Most major chains like CVS and Walgreens are included, but smaller pharmacies may not be. Always confirm before filling a prescription. For long-term medications, mail-order services often offer lower copays and 90-day supplies.

What is Extra Help, and do I qualify?

Extra Help (Low-Income Subsidy) is a federal program that lowers prescription costs for people with limited income. If you have full Medicaid coverage, you automatically qualify. Benefits include $0 premiums, $0 deductibles, $4.90 copays for generics, and $12.15 for brand-name drugs. After spending $2,000 in a year, you pay nothing. About 1.2 million eligible people don’t know they qualify - check with Medicaid or call 1-800-MEDICARE.

Why do Medicaid formularies change so often?

Formularies change because drug prices shift, rebates expire, and new generics enter the market. States update lists to save money - often removing drugs that no longer offer financial rebates from manufacturers. North Carolina, for example, removed 12 drugs in 2025 because they were no longer rebate-eligible. Always check your formulary every 6 months.

Are over-the-counter drugs covered by Medicaid?

Generally, no. Medicaid doesn’t cover OTC drugs unless they’re prescribed by a doctor and meet specific medical criteria - which is rare. Even then, coverage varies by state. Always ask your pharmacist or Medicaid office before assuming an OTC drug is covered.