Sertraline is a commonly prescribed SSRI antidepressant. Doctors use it for major depression, panic disorder, social anxiety, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). It helps balance serotonin in the brain, which can lift mood, lower anxiety, and reduce compulsive thoughts or panic attacks.
Most adults start at 50 mg once a day, usually in the morning or at night depending on how it affects you. Some people begin at 25 mg to reduce early side effects, then move up. Typical dosing ranges from 25 mg to 200 mg daily for adults, but your doctor will choose the right dose for your condition.
Expect to wait 4–6 weeks to feel the main benefits. Small improvements may show earlier, but full effect takes time. Take it the same way every day — with or without food — and try to keep a steady schedule. If a dose is missed, take it when you remember unless it's almost time for the next dose; then skip the missed one. Never double up without medical advice.
Common side effects include nausea, diarrhea, headaches, trouble sleeping or feeling sleepy, and sexual side effects like lower libido or delayed orgasm. Most side effects ease after a few weeks. Serious but rare issues include serotonin syndrome (agitation, high fever, tremor, fast heartbeat), low sodium (especially in older adults), and unusual bleeding when combined with NSAIDs or blood thinners.
Do not take sertraline with monoamine oxidase inhibitors (MAOIs) or within two weeks of stopping an MAOI. Be cautious with other serotonergic drugs, triptans, and certain herbal products like St. John’s wort. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor — sometimes sertraline is chosen because its risks are better understood, but decisions are personal and medical.
Watch mood and behavior closely, especially in young adults and teens. Any new or worsening suicidal thoughts, agitation, or severe mood changes require immediate contact with a healthcare professional.
If you need to stop sertraline, your doctor will usually recommend a slow taper to reduce withdrawal-like symptoms such as dizziness, irritability, or flu-like feelings. Don’t stop suddenly unless instructed by a clinician.
Buying sertraline online safely: always use a licensed pharmacy and keep your prescription. Check that the online pharmacy lists a physical address, phone number, and requires a prescription. Look for accreditation badges (like NABP/Verified Internet Pharmacy Practice Sites or LegitScript) and read user reviews. Beware of sites selling without prescription or offering unusually low prices — those pills may be unsafe or counterfeit. When in doubt, ask your prescribing doctor which options are reputable or use local pharmacies to fill your prescription.
Questions about interactions, side effects, or dosing should go to your prescriber or pharmacist. Sertraline works well for many people when used correctly and monitored responsibly.
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